MGI phenotypes (gene matching)
STOCK Smad9tm2Rob/H
| Status | Available to order |
| EMMA ID | EM:02524 |
| Citation information | RRID:IMSR_EM:02524 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Smad9tm2Rob/H |
| Alternative name | Smad8 Conditional |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Smad9tm2Rob |
| Gene/Transgene symbol | Smad9 |
Information from provider
| Provider | Elizabeth Robertson |
| Provider affiliation | Sir William Dunn School of Pathology, University of Oxford |
| Genetic information | Knock in of loxP flanked exon 2-3 locus at the Smad8 locus enables conditional inactivation of Smad8 in vivo via Cre mediated recombination and excision of Smad8 coding sequences. |
| Phenotypic information | No overt phenotype. |
| Breeding history | Outcrossed to CD1. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Literature references
- Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo.;Arnold Sebastian J, Maretto Silvia, Islam Ayesha, Bikoff Elizabeth K, Robertson Elizabeth J, ;2006;Developmental biology;296;104-18; 16765933