STOCK T(2;8)2Wa/H

Status

Available to order

EMMA IDEM:02584
Citation informationRRID:IMSR_EM:02584 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameSTOCK T(2;8)2Wa/H
Alternative nameT(2;8)2Wa
Strain typeChromosomal Anomalies
Allele/Transgene symbolT(2;8)2Wa, at, Bloc1s6pa, Edn3ls
Gene/Transgene symbolT(2;8)2Wa, a, Bloc1s6, Edn3

Information from provider

ProviderColin Beechey
Provider affiliationMRC Harwell, Didcot, Oxon, OX11 0RD
Genetic informationReciprocal translocation of chromosomes 2 and 8 with breakpoints similar to those of T(2;8)26H. Breakpoints are at 2H3 and 8A4 (the Chr 2 breakpoint is at distal H3). Used to determine the Chr 2 distal imprinting region.
Phenotypic informationHomozygotes have pallid coat colouration.
Breeding historyInbred
References
  • Mapping studies of the distal imprinting region of mouse chromosome 2.;Peters J, Beechey C V, Ball S T, Evans E P, ;1994;Genetical research;63;169-74; 8082833
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal skin morphology / IMPC
  • abnormal skin morphology / IMPC
  • abnormal eye morphology / IMPC
  • abnormal coat/hair pigmentation / IMPC
  • cataract / IMPC
  • enlarged heart / IMPC
  • increased circulating serum albumin level / IMPC
  • hyperactivity / IMPC
  • abnormal kidney morphology / IMPC
  • abnormal vitreous body morphology / IMPC
  • abnormal heart morphology / IMPC
  • abnormal spleen morphology / IMPC
  • abnormal lymph node morphology / IMPC
  • small kidney / IMPC
  • enlarged spleen / IMPC
MGI phenotypes (gene matching)
  • increased brown adipose tissue amount / MGI
  • irregular coat pigmentation / MGI
  • mottled coat / MGI
  • pigmentation phenotype / MGI
  • increased body length / MGI
  • increased body weight / MGI
  • obese / MGI
  • hypoactivity / MGI
  • abnormal coat appearance / MGI
  • hyperglycemia / MGI
  • increased urine glucose level / MGI
  • neoplasm / MGI
  • increased tumor incidence / MGI
  • decreased incidence of induced tumors / MGI
  • abnormal coat/hair pigmentation / MGI
  • increased circulating insulin level / MGI
  • prenatal lethality / MGI
  • abnormal skin pigmentation / MGI
  • abnormal lipid homeostasis / MGI
  • no abnormal phenotype detected / MGI
  • abnormal renal tubule morphology / MGI
  • dilated renal tubules / MGI
  • increased liver weight / MGI
  • maternal imprinting / MGI
  • yellow coat color / MGI
  • phenotypic reversion / MGI
  • maternal effect / MGI
  • embryonic growth retardation / MGI
  • abnormal hair follicle melanogenesis / MGI
  • decreased circulating pituitary hormone level / MGI
  • abnormal pancreatic islet morphology / MGI
  • impaired glucose tolerance / MGI
  • abnormal renal glomerulus morphology / MGI
  • insulin resistance / MGI
  • variegated coat color / MGI
  • endocrine/exocrine gland phenotype / MGI
  • darkened coat color / MGI
  • abnormal food intake / MGI
  • increased susceptibility to weight gain / MGI
  • increased percent body fat/body weight / MGI
  • increased circulating leptin level / MGI
  • abnormal ventral coat pigmentation / MGI
  • abnormal dorsoventral coat patterning / MGI
  • abnormal adrenal gland x-zone morphology / MGI
  • embryonic lethality / MGI
  • degranulated pancreatic beta cells / MGI
  • increased gonadal fat pad weight / MGI
  • increased inguinal fat pad weight / MGI
  • increased retroperitoneal fat pad weight / MGI
  • abnormal pinna hair pigmentation / MGI
  • abnormal tail hair pigmentation / MGI
  • increased total body fat amount / MGI
  • mortality/aging / MGI
  • integument phenotype / MGI
  • embryonic lethality at implantation, complete penetrance / MGI
  • embryonic lethality between implantation and placentation, complete penetrance / MGI
  • expanded mesangial matrix / MGI
  • renal cast / MGI
  • increased renal glomerulus basement membrane thickness / MGI
  • increased food intake / MGI
  • abnormal epigenetic regulation of gene expression / MGI

Literature references

  • Mapping studies of the distal imprinting region of mouse chromosome 2.;Peters J, Beechey C V, Ball S T, Evans E P, ;1994;Genetical research;63;169-74; 8082833

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
Not found what you were looking for? Search here for other strains available from EMMA.


Search
INFRAFRONTIER® and European Mouse Mutant Archive - EMMA® are registered trademarks at the European Union Intellectual Property Office (EUIPO).