C3H;C-Rps7Mtu/H

Status

Available to order

EMMA IDEM:02585
Citation informationRRID:IMSR_EM:02585 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameC3H;C-Rps7Mtu/H
Alternative nameMontu
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolRps7Mtu
Gene/Transgene symbolRps7

Information from provider

ProviderDebora Bogani
Provider affiliationMammalian Genetics Unit, MRC Harwell
Genetic informationMutation maps to chromosome 12, proximal of D12Mit239.
Phenotypic informationHeterozygotes exhibit abnormal tail morphology, are deaf and have belly spots that are characteristic of neural crest defects. Homozygotes, do not appear to be viable, as they have an open neural tube.
Breeding historyBackcrossed to C3H/HeH.
References
  • New semidominant mutations that affect mouse development.;Bogani Debora, Warr Nick, Elms Paul, Davies Jennifer, Tymowska-Lalanne Zuzanna, Goldsworthy Michelle, Cox Roger D, Keays David A, Flint Jonathan, Wilson Valerie, Nolan Pat, Arkell Ruth, ;2004;Genesis (New York, N.Y. : 2000);40;109-117; 15384171
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

MGI phenotypes (allele matching)
  • premature death / MGI
  • belly spot / MGI
  • kinked tail / MGI
  • decreased body size / MGI
  • increased mean corpuscular volume / MGI
  • curly tail / MGI
  • abnormal vertebral arch morphology / MGI
  • decreased vertebrae number / MGI
  • thin cerebral cortex / MGI
  • abnormal spatial working memory / MGI
  • enlarged brain ventricles / MGI
  • abnormal hindbrain morphology / MGI
  • decreased neural crest cell number / MGI

Literature references

  • New semidominant mutations that affect mouse development.;Bogani Debora, Warr Nick, Elms Paul, Davies Jennifer, Tymowska-Lalanne Zuzanna, Goldsworthy Michelle, Cox Roger D, Keays David A, Flint Jonathan, Wilson Valerie, Nolan Pat, Arkell Ruth, ;2004;Genesis (New York, N.Y. : 2000);40;109-117; 15384171

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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Practical information

Example health report
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