B6Ola.129S2-Gpi1a/Gpi1b/WsH

Status

Available to order

EMMA IDEM:02609
Citation informationRRID:IMSR_EM:02609 

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International strain nameB6Ola.129S2-Gpi1a/Gpi1b/WsH
Alternative nameC57BL/Ola.129-Gpi1-sa/Ws
Strain typeOther
Allele/Transgene symbolGpi1a, Gpi1b
Gene/Transgene symbolGpi1, Gpi1

Information from provider

ProviderJohn West
Provider affiliationGenes and Development Group, University of Edinburgh
Genetic informationElectrophoretic variant. Gpi1-sa allele from 129/Sv-CP/Pas-VeFuKi congenic on C57BL/6Ola. Gpi1-sa is a common allele but C57BL congenic strains are a useful resource for transplantation experiments etc.
Phenotypic informationElectrophoretic variant of Gpi1-sa.
Breeding historyGpi1-sa allele from 129/Sv-CP/Pas-VeFuKi congenic on C57BL/6Ola. Offspring will be heterozygous: Gpi1-sb/Gpi1-sa
References
  • Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus).;DeLorenzo R J, Ruddle F H, ;1969;Biochemical genetics;3;151-62; 5364923
  • Genetic differences in glucose phosphate isomerase activity among mouse embryos.;West J D, Flockhart J H, ;1989;Development (Cambridge, England);107;465-72; 2612373
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased hematocrit / MGI
  • decreased body weight / MGI
  • prenatal lethality / MGI
  • abnormal embryonic tissue morphology / MGI
  • abnormal erythrocyte morphology / MGI
  • increased mean corpuscular volume / MGI
  • reticulocytosis / MGI
  • increased heart weight / MGI
  • decreased erythrocyte cell number / MGI
  • increased liver weight / MGI
  • abnormal erythrocyte physiology / MGI
  • abnormal erythrocyte osmotic lysis / MGI
  • increased spleen weight / MGI
  • increased circulating bilirubin level / MGI
  • increased circulating glucose level / MGI
  • decreased mean corpuscular hemoglobin / MGI
  • abnormal enzyme/coenzyme activity / MGI
  • increased lung weight / MGI
  • decreased mean corpuscular hemoglobin concentration / MGI
  • lethality, incomplete penetrance / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality between implantation and placentation, complete penetrance / MGI
  • preweaning lethality, complete penetrance / MGI

Literature references

  • Genetic control of two electrophoretic variants of glucosephosphate isomerase in the mouse (Mus musculus).;DeLorenzo R J, Ruddle F H, ;1969;Biochemical genetics;3;151-62; 5364923
  • Genetic differences in glucose phosphate isomerase activity among mouse embryos.;West J D, Flockhart J H, ;1989;Development (Cambridge, England);107;465-72; 2612373

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

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