B6.Cg-Tg(B2m-lacZ)2Cba/CbaOrl
| Status | Available to order |
| EMMA ID | EM:00028 |
| Citation information | RRID:IMSR_EM:00028 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(B2m-lacZ)2Cba/CbaOrl |
| Alternative name | beta2m LacZ |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(B2m-lacZ)2Cba |
| Gene/Transgene symbol | Tg(B2m-lacZ)2Cba |
Information from provider
| Provider | Charles BABINET |
| Provider affiliation | Institut Pasteur |
| Genetic information | Transgenic mice expressing the E. coli lacZ gene under the control of the beta2 microglobulin promoter. This expression can be easily monitored with a beta-galactosidase coloration. |
| Phenotypic information | B2m-lacZ mice are viable, suggesting that these transgenes are sensitive to position effect; lacZ expression is controlled by endogenous chromosomal regulatory elements specific for each insertion site. |
| Breeding history | (C57BL/6 X SJL/J) origin; 10 generations of backcross to C57BL/6 and then intercross. Breeding at heterozygous state. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Literature references
- Unexpected position-dependent expression of H-2 and beta 2-microglobulin/lacZ transgenes.;Cohen-Tannoudji M, Morello D, Babinet C, ;1992;Molecular reproduction and development;33;149-59; 1418983