MGI phenotypes (gene matching)
B6.129S4-Gp5tm1Cgh/Orl
| Status | Available to order |
| EMMA ID | EM:00393 |
| Citation information | RRID:IMSR_EM:00393 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S4-Gp5tm1Cgh/Orl |
| Alternative name | B6.129-Gp5tm |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Gp5tm1Cgh |
| Gene/Transgene symbol | Gp5 |
Information from provider
| Provider | Francois Lanza |
| Provider affiliation | UMR Inserm UdS 949, EFS-Alsace |
| Genetic information | See ref.: Kahn ML et al. Blood. 1999 Dec 15;94(12):4112-21. |
| Phenotypic information | Defective platelet functions, decreased collagen response, increased thrombin response. |
| Breeding history | Backcrossed to C57BL/6J for 7 generations. Mating: 1 knock-out male x 2 knock-out females |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Disease and phenotype information
Literature references
- Glycoprotein V-deficient platelets have undiminished thrombin responsiveness and Do not exhibit a Bernard-Soulier phenotype.;Kahn M L, Diacovo T G, Bainton D F, Lanza F, Trejo J, Coughlin S R, ;1999;Blood;94;4112-21; 10590056