B6;129-Agr2tm1Kuv/Orl

Status

Available to order

EMMA IDEM:04307
Citation informationRRID:IMSR_EM:04307 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6;129-Agr2tm1Kuv/Orl
Alternative nameB6.129Sv/Pas-Agr2tm
Strain typeTargeted Mutant Strains : Conditional mutation
Allele/Transgene symbolAgr2tm1Kuv
Gene/Transgene symbolAgr2

Information from provider

ProviderPhilip ROSENSTIEL
Provider affiliationIKMB, University of Kiel
Genetic informationConditional deletion of the translation start by insertion of two loxP sites flanking exons 2 to 4. Details available upon request.
Phenotypic informationNot known.
Breeding historyBackcrossed to C57BL/6 for less than 5 generations.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France
Animals used for archivingheterozygous males, wild-type C57BL/6J females

Disease and phenotype information

MGI phenotypes (gene matching)
  • increased mast cell number / MGI
  • increased cell proliferation / MGI
  • abnormal stomach glandular epithelium morphology / MGI
  • abnormal enterocyte morphology / MGI
  • abnormal large intestine morphology / MGI
  • rectal prolapse / MGI
  • abnormal small intestine morphology / MGI
  • abnormal intestinal mucosa morphology / MGI
  • decreased body weight / MGI
  • anemia / MGI
  • premature death / MGI
  • abnormal Peyer's patch follicle morphology / MGI
  • colitis / MGI
  • intestinal obstruction / MGI
  • abnormal intestinal goblet cell morphology / MGI
  • abnormal female reproductive system physiology / MGI
  • enlarged stomach / MGI
  • abnormal gastric parietal cell morphology / MGI
  • abnormal gastric chief cell morphology / MGI
  • abnormal large intestine crypts of Lieberkuhn morphology / MGI
  • decreased circulating serum albumin level / MGI
  • increased susceptibility to induced colitis / MGI
  • decreased total fat pad weight / MGI
  • ileum inflammation / MGI
  • abnormal intestine physiology / MGI
  • stomach mucosa hyperplasia / MGI
  • abnormal stomach enteroendocrine cell morphology / MGI
  • increased Paneth cell number / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

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