IMPC phenotypes (gene matching)
B6;129-Nell1tm1Kuv/Orl
| Status | Available to order |
| EMMA ID | EM:04309 |
| Citation information | RRID:IMSR_EM:04309 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Nell1tm1Kuv/Orl |
| Alternative name | B6.129Sv/Pas-Nell1tm |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Nell1tm1Kuv |
| Gene/Transgene symbol | Nell1 |
Information from provider
| Provider | Philip ROSENSTIEL |
| Provider affiliation | IKMB, University of Kiel |
| Genetic information | Conditional deletion of the translation start by insertion of two loxP sites flanking exon 1. Details available upon request. |
| Phenotypic information | Not known. |
| Breeding history | Backcrossed to C57BL/6 for less than 5 generations. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous males, wild-type C57BL/6J females |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased bone mineral density / MGI
- abnormal neurocranium morphology / MGI
- megacephaly / MGI
- respiratory failure / MGI
- abnormal reflex / MGI
- abnormal axial skeleton morphology / MGI
- abnormal bone mineralization / MGI
- abnormal cervical vertebrae morphology / MGI
- abnormal intervertebral disk morphology / MGI
- abnormal spine curvature / MGI
- enlarged frontal bone / MGI
- enlarged interparietal bone / MGI
- enlarged parietal bone / MGI
- enlarged nasal bone / MGI
- abnormal vertebrae development / MGI
- abnormal intervertebral disk development / MGI
- perinatal lethality, complete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- preweaning lethality, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- decreased bone ossification / MGI
- thin frontal bone / MGI
- thin interparietal bone / MGI
- thin parietal bone / MGI