B6.129P2-Cstbtm2Yah/Orl

Status

Available to order

EMMA IDEM:04463
Citation informationRRID:IMSR_EM:04463 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6.129P2-Cstbtm2Yah/Orl
Alternative nameCSTB<5HP>
Strain typeTargeted Mutant Strains : Other targeted
Allele/Transgene symbolCstbtm2Yah
Gene/Transgene symbolCstb

Information from provider

ProviderYann Herault
Provider affiliationCNRS IEM UMR 6218
Genetic informationInsertion by homologous recombination of a targeting vector containing loxP site in the locus of Cstb gene (MMU10), with duplication of this gene.
Phenotypic informationDuplication of the Cstb gene.
ReferencesNone available
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France
Animals used for archivinghomozygous C57BL/6J males, wild-type C57BL/6J females

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)
  • decreased body length / IMPC
  • increased monocyte cell number / IMPC
  • abnormal auditory brainstem response / IMPC
  • decreased total retina thickness / IMPC
  • abnormal eye anterior chamber depth / IMPC
  • abnormal retina outer nuclear layer morphology / IMPC
  • decreased lymphocyte cell number / IMPC
  • hyperactivity / IMPC
  • increased vertical activity / IMPC
  • short tibia / IMPC
  • increased circulating triglyceride level / IMPC
  • decreased circulating creatinine level / IMPC
MGI phenotypes (gene matching)
  • myoclonus / MGI
  • abnormal cerebellum morphology / MGI
  • cerebellum hypoplasia / MGI
  • abnormal cornea morphology / MGI
  • increased incidence of corneal inflammation / MGI
  • corneal opacity / MGI
  • corneal scarring / MGI
  • ataxia / MGI
  • impaired coordination / MGI
  • abnormal gait / MGI
  • abnormal apoptosis / MGI
  • seizures / MGI
  • nervous system phenotype / MGI
  • abnormal nervous system physiology / MGI
  • abnormal cerebellar granule cell morphology / MGI
  • abnormal brain wave pattern / MGI
  • abnormal eye physiology / MGI
  • growth/size/body region phenotype / MGI
  • behavior/neurological phenotype / MGI
  • uveitis / MGI
  • facial muscle spasm / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
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