| Status | Available to order |
| EMMA ID | EM:04538 |
| Citation information | RRID:IMSR_EM:04538 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S7(Cg)-Syce1tm1Hgu/H |
| Alternative name | Syce1KO /C57Bl6 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Syce1tm1Hgu |
| Gene/Transgene symbol | Syce1 |
| Provider | Howard Cooke |
| Provider affiliation | Department of Medical & Developmental Genetics, MRC Human Genetics Unit |
| Genetic information | Exons 2 through 11 were replaced with an IRES/lacZ and floxed neo cassette. |
| Phenotypic information | Mice homozygous for this mutation in this background can not progress to diplotene stages of meiosis and show a failure of synapsis. Heterozygous mice show close to normal fertility. |
| Breeding history | Founder males were initially crossed onto CD1 outbred females. Subsequently males were backcrossed 8 generations to C57BL/6J. |
| References |
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| Homozygous fertile | no |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6J males |
| Breeding at archiving centre | None. Males were archived at the time of arrival at the archiving centre. |
Orphanet associated rare diseases, based on orthologous gene matching
