IMPC phenotypes (gene matching)
B6;129-Nlrx1tm1.1Kuv/Orl
| Status | Available to order |
| EMMA ID | EM:04539 |
| Citation information | RRID:IMSR_EM:04539 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;129-Nlrx1tm1.1Kuv/Orl |
| Alternative name | B6.129Sv-Nlrx1tm1 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Nlrx1tm1.1Kuv |
| Gene/Transgene symbol | Nlrx1 |
Information from provider
| Provider | Philip ROSENSTIEL |
| Provider affiliation | IKMB, University of Kiel |
| Genetic information | Details available upon request. |
| Phenotypic information | Not known. |
| Breeding history | Backcrossed to C57BL/6 for less than 5 generations. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased body weight / MGI
- increased susceptibility to viral infection / MGI
- abnormal macrophage physiology / MGI
- abnormal neutrophil physiology / MGI
- increased interferon-beta secretion / MGI
- increased circulating interleukin-6 level / MGI
- increased interleukin-1 beta secretion / MGI
- increased interleukin-6 secretion / MGI
- increased susceptibility to endotoxin shock / MGI