IMPC phenotypes (gene matching)
B6.129S2-Cbx5Gt(W205C07)Wrst/Ieg
| Status | Available to order |
| EMMA ID | EM:04623 |
| Citation information | RRID:IMSR_EM:04623 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Cbx5Gt(W205C07)Wrst/Ieg |
| Alternative name | C57BL/6-TgR(Cbx5)W205C07 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Cbx5Gt(W205C07)Wrst |
| Gene/Transgene symbol | Cbx5 |
Information from provider
| Provider | Harald von Melchner |
| Provider affiliation | University of Frankfurt Medical School |
| Additional owner | Generated by Prof. Harald von Melchner as part of the German Gene Trap Consortium |
| Genetic information | Knock-out by integration of the ROSAbetageo gene trap into intron 1 of the Cbx5 gene. |
| Phenotypic information | Homozygous mice do not show any obvious phenotype. Double mutants with a hypomorphic knock-out for Cbx1 (Cbx1Gt(U3Betageo)1Ruiz, MGI:2678420) are early embryonic lethal. |
| Breeding history | More than 5 backcrosses onto C57BL/6, currently kept further by C57BL/6 backcrossing. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583