MGI phenotypes (allele matching)
- no phenotypic analysis / MGI
B6.129S2-Nkain4Gt(M076C04)Vmel/Ieg
| Status | Available to order |
| EMMA ID | EM:04625 |
| Citation information | RRID:IMSR_EM:04625 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Nkain4Gt(M076C04)Vmel/Ieg |
| Alternative name | C57BL/6-TgR(Nkain4)M076C04 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Nkain4Gt(M076C04)Vmel |
| Gene/Transgene symbol | Nkain4 |
Information from provider
| Provider | Harald von Melchner |
| Provider affiliation | University of Frankfurt Medical School |
| Additional owner | Generated by Prof. Harald von Melchner as part of the German Gene Trap Consortium |
| Genetic information | Knock-out by integration of the U3Ceo gene trap into intron 1 of the Nkain4 gene. |
| Phenotypic information | Homozygous mice do not show any gross phenotypical abnormalities. Phenotype as analyzed by the German Mouse Clinic (www.mouseclinic.de) will be reported in the Phenome database. |
| Breeding history | More than 5 backcrosses onto C57BL/6; currently further kept by alternating C57BL/6 backcrossing and homozygous intercrosses. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
Disease and phenotype information
MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
Literature references
- The essential function of HP1 beta: a case of the tail wagging the dog?;Billur Mustafa, Bartunik Hans D, Singh Prim B, ;2010;Trends in biochemical sciences;35;115-23; 19836960
- High-throughput trapping of secretory pathway genes in mouse embryonic stem cells.;De-Zolt Silke, Schnütgen Frank, Seisenberger Claudia, Hansen Jens, Hollatz Melanie, Floss Thomas, Ruiz Patricia, Wurst Wolfgang, von Melchner Harald, ;2006;Nucleic acids research;34;e25; 16478711