MGI phenotypes (allele matching)
- no phenotypic analysis / MGI
B6.192P2-Zfp647Gt(ES492)Hgs/H
| Status | Available to order |
| EMMA ID | EM:04662 |
| Citation information | RRID:IMSR_EM:04662 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.192P2-Zfp647Gt(ES492)Hgs/H |
| Alternative name | Zfp647Gt(betageo)1Hgs C57BL/6 |
| Strain type | Gene-trap |
| Allele/Transgene symbol | Zfp647Gt(ES492)Hgs |
| Gene/Transgene symbol | Zfp647 |
Information from provider
| Provider | Heidi Sutherland |
| Provider affiliation | MRC Human Genetics Unit, Institute of Genetics and Molcular Medicine |
| Genetic information | The Zfp647 locus was disrupted by the insertion into exon 5 of the gene trap-vector pGT1-3 containing a beta-geo cassette. |
| Phenotypic information | Homozygotes are embryonic lethal before 6.5 dpc. |
| Breeding history | Chimeras have been backcrossed to C57BL/6 for more than 10 generations. |
| References |
|
| Homozygous fertile | no |
| Homozygous viable | no |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
| Animals used for archiving | heterozygous C57BL/6 males |
| Breeding at archiving centre | None |
Disease and phenotype information
MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
Literature references
- The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin.;Nagano Takashi, Mitchell Jennifer A, Sanz Lionel A, Pauler Florian M, Ferguson-Smith Anne C, Feil Robert, Fraser Peter, ;2008;Science (New York, N.Y.);322;1717-20; 18988810
- KRAB zinc-finger proteins localise to novel KAP1-containing foci that are adjacent to PML nuclear bodies.;Briers Stephanie, Crawford Catherine, Bickmore Wendy A, Sutherland Heidi G, ;2009;Journal of cell science;122;937-46; 19258395