| Status | Available to order |
| EMMA ID | EM:04764 |
| Citation information | RRID:IMSR_EM:04764 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Tyrc-m/Cnbc |
| Alternative name | Tyr |
| Strain type | Induced Mutant Strains : Radiation-induced |
| Allele/Transgene symbol | Tyrc-m, Tyrc |
| Gene/Transgene symbol | Tyr, Tyr |
| Provider | Lluis Montoliu |
| Provider affiliation | Departamento de Biologia Molecular y Celular, CNB-CSIC, Centro Nacional de Biotecnologia |
| Additional owner | The original Tyr |
| Genetic information | Mice carrying the Tyrc-m "chinchilla mottled" allele were imported as live animals from MRC Harwell (FESA), Peter Glenister, in 2001 after rescuing the line from frozen embryos. Genotype received included: Tyrc-m/Tyrc-m, a/a, +/Ednrbs. Since then they were bred to albino outbred Hsd:NMRI mice and eventually maintained as homozygous Tyrc-m/Tyrc-m. |
| Phenotypic information | Tyrc-m "chinchilla mottled" mice have dark and light mottled coat, usually seen as "stripes or patches". Homozygous are darker (more pigmented) than heterozygous, which appear to be light grey. |
| Breeding history | Since 2001, the Tyrsupc-m/sup chinchilla mottled allele it has been bred and maintained, as homozygous, in albino outbred Hsd:NMRI mouse strain. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | homozygous NMRI males, wild-type NMRI females |
| Stage of embryos | 8-cell |
Orphanet associated rare diseases, based on orthologous gene matching
