| Status | Available to order |
| EMMA ID | EM:04973 |
| Citation information | RRID:IMSR_EM:04973 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129(C)-Hmox1tm1.1Gkl/Flmg |
| Alternative name | Hmox1FL/FL, HO-1FL/FL |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Hmox1tm1.1Gkl |
| Gene/Transgene symbol | Hmox1 |
| Provider | George Kollias |
| Provider affiliation | B.S.R.C. |
| Genetic information | This strain carries a conditional mutation of Hmox1. Specifically, exons 3 and 4 are flanked with loxP sites. Mating this strain with any cre recombinase transgenic strain will result in the inactivation of Hmox1 wherever cre recombinase is expressed. |
| Phenotypic information | Cell specific ablation of heme oxygenase 1 (Hmox1) upon cre recombination. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | B.S.R.C. Alexander Fleming, Vari, Greece |
| Animals used for archiving | homozygous C57BL/6.129/Sv males, wild-type C57BL/6 females |
| Stage of embryos | 8-cell |
Orphanet associated rare diseases, based on orthologous gene matching
