FVB/N-Tg(Cnp-TVA,-lacZ)B8Ubc/Kctt
| Status | Available to order |
| EMMA ID | EM:04993 |
| Citation information | RRID:IMSR_EM:04993 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | FVB/N-Tg(Cnp-TVA,-lacZ)B8Ubc/Kctt |
| Alternative name | Ctv-a wild type |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Cnp-TVA,-lacZ)B8Ubc |
| Gene/Transgene symbol | Tg(Cnp-TVA,-lacZ)B8Ubc |
Information from provider
| Provider | Lene Uhrbom |
| Provider affiliation | Department of Neuroscience, Uppsala University |
| Additional owner | Lene Uhrbom, Uppsala University, Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala, Sweden |
| Genetic information | Transgenic construct: pCNPase-TV-A-IRES-lacZ, made in FVB/N. |
| Phenotypic information | Allows for infection of 2',3'-cyclic nucleotide 3' phosphodiesterase (CNPase)-expressing cells by RCAS virus. |
| Breeding history | The founder mouse was crossed with FVB/N and subsequently intercrossed. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous males, wild-type FVB/N females |
| Breeding at archiving centre | No breeding at Karolinska Inst. Last IVF was made from re-derived embryos. |
| Stage of embryos | 2-cell |
Literature references
- Oligodendrocyte progenitor cells can act as cell of origin for experimental glioma.;Lindberg N, Kastemar M, Olofsson T, Smits A, Uhrbom L, ;2009;Oncogene;28;2266-75; 19421151