CBACa;129P2-Kctd10Gt(RRG305)Byg/WtsiCnbc

Status

Available to order

EMMA IDEM:05012
Citation informationRRID:IMSR_EM:05012 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameCBACa;129P2-Kctd10Gt(RRG305)Byg/WtsiCnbc
Alternative nameKctd10 genetrap
Strain typeGene-trap
Allele/Transgene symbolKctd10Gt(RRG305)Byg
Gene/Transgene symbolKctd10

Information from provider

ProviderKaren Steel
Provider affiliationWellcome Trust Sanger Institute
Genetic informationThis line is derived from a standard genetrap using vector pGT0Lxf from BayGenomics.
Phenotypic informationNo obvious phenotype in heterozygotes other than carpel fusion, but homozygotes are lethal before birth around E10.5.
Breeding historyChimaeras derived from microinjection of the genetrapped ES cell were mated with CBA/Ca and hets were intercrossed to establish the colony.
ReferencesNone available
Homozygous fertileno
Homozygous viableno
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain

Disease and phenotype information

IMPC phenotypes (allele matching)
  • abnormal radius morphology / IMPC
  • trunk curl / IMPC
  • abnormal joint morphology / IMPC
  • decreased circulating chloride level / IMPC
  • decreased circulating sodium level / IMPC
  • decreased grip strength / IMPC
  • preweaning lethality, complete penetrance / IMPC
IMPC phenotypes (gene matching)
  • decreased grip strength / IMPC
  • decreased circulating sodium level / IMPC
  • abnormal joint morphology / IMPC
  • abnormal radius morphology / IMPC
  • decreased circulating chloride level / IMPC
  • trunk curl / IMPC
  • preweaning lethality, complete penetrance / IMPC
MGI phenotypes (gene matching)
  • abnormal angiogenesis / MGI
  • abnormal heart valve morphology / MGI
  • enlarged pericardium / MGI
  • abnormal artery morphology / MGI
  • thin myocardium / MGI
  • no phenotypic analysis / MGI
  • abnormal vitelline vasculature morphology / MGI
  • abnormal umbilical artery morphology / MGI
  • embryonic growth retardation / MGI
  • abnormal vitelline vascular remodeling / MGI
  • abnormal cardinal vein morphology / MGI
  • abnormal dorsal aorta morphology / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • abnormal internal carotid artery morphology / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

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