STOCK Rffltm1Cota/Orl

Status

Available to order

EMMA IDEM:05207
Citation informationRRID:IMSR_EM:05207 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameSTOCK Rffltm1Cota/Orl
Alternative nameRffltßgeo
Strain typeTargeted Mutant Strains : Knock-out
Allele/Transgene symbolRffltm1Cota
Gene/Transgene symbolRffl

Information from provider

ProviderMichel Cohen-Tannoudji
Provider affiliationDepartement de Biologie du Développement, Unite de Génétique Fonctionnelle de la Souris, URA 2578 CNRS/Institut Pasteur
Genetic informationIn frame fusion of the ßgeo protein with the first fourteen amino acids of Rffl.
Phenotypic informationNo obvious phenotype.
Breeding historyThe strain is maintained through mating of homozygous animals.
References
  • CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.;Ahmed Afsar U, Moulin Maryline, Coumailleau Franck, Wong W Wei-Lynn, Miasari Maria, Carter Holly, Silke John, Cohen-Tannoudji Michel, Vince James E, Vaux David L, ;2009;Current biology : CB;19;R15-7; author reply R17-9; 19138581
Homozygous fertileyes
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreCNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France
Animals used for archivingheterozygous C57BL/6.CBA males, wild-type C57BL/6.CBA females

Disease and phenotype information

IMPC phenotypes (gene matching)
  • abnormal thymus morphology / IMPC
  • abnormal heart morphology / IMPC
  • enlarged thymus / IMPC
  • enlarged spleen / IMPC
  • abnormal heart shape / IMPC
  • abnormal spleen morphology / IMPC
MGI phenotypes (gene matching)
  • no abnormal phenotype detected / MGI

Literature references

  • CARP2 deficiency does not alter induction of NF-kappaB by TNFalpha.;Ahmed Afsar U, Moulin Maryline, Coumailleau Franck, Wong W Wei-Lynn, Miasari Maria, Carter Holly, Silke John, Cohen-Tannoudji Michel, Vince James E, Vaux David L, ;2009;Current biology : CB;19;R15-7; author reply R17-9; 19138581

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.​
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