B6;CBACa-Tg(CMV-GAL4)1Wrk/H

Status

Available to order

EMMA IDEM:05363
Citation informationRRID:IMSR_EM:05363 

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International strain nameB6;CBACa-Tg(CMV-GAL4)1Wrk/H
Alternative nameCMV Gal4
Strain typeTransgenic Strains
Allele/Transgene symbolTg(CMV-GAL4)1Wrk
Gene/Transgene symbolTg(CMV-GAL4)1Wrk

Information from provider

ProviderWolf Reik
Provider affiliationLaboratory of Imprinting and Development Genetics
Genetic informationCMV promotor driving Gal4 expression. This transgenic strain was made so that Gal4-myc fusion protein is ubiquitously expressed. In combination with transgenic or knock-in strains carrying the target sequence for Gal4 (UAS) the Gal4-myc fusion protein is targeted to the predetermined location with the UAS target site.
Phenotypic informationNo overt phenotype.
Breeding historyMaintained by intercrossing heterozygous animals.
References
  • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops.;Murrell Adele, Heeson Sarah, Reik Wolf, ;2004;Nature genetics;36;889-93; 15273689
Homozygous fertilenot known
Homozygous viableyes
Homozygous matings requiredno
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom
Animals used for archivingheterozygous (C57BL/6J x CBA/Ca)F1 males, heterozygous (C57BL/6J x CBA/Ca)F1 females
Breeding at archiving centreNo breeding was performed at the archiving centre.
Stage of embryos8-cell

Literature references

  • Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loops.;Murrell Adele, Heeson Sarah, Reik Wolf, ;2004;Nature genetics;36;889-93; 15273689

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

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