IMPC phenotypes (gene matching)
B6.129-P2ry14tm1Gac/Orl
| Status | Available to order |
| EMMA ID | EM:05368 |
| Citation information | RRID:IMSR_EM:05368 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-P2ry14tm1Gac/Orl |
| Alternative name | P2Y14 Lox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | P2ry14tm1Gac |
| Gene/Transgene symbol | P2ry14 |
Information from provider
| Provider | Christian Gachet |
| Provider affiliation | UMR Inserm UdS 949, EFS-Alsace |
| Genetic information | Insertion of loxP sites from part to part of P2Y14 exon coding sequence. |
| Phenotypic information | None observed so far. |
| Breeding history | 10 backcrosses with C57BL/6J mice. |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
| Animals used for archiving | homozygous C57BL/6J males, wild-type C57BL/6J females |
Disease and phenotype information
MGI phenotypes (gene matching)
- abnormal muscle physiology / MGI
- decreased airway responsiveness / MGI
- increased heart rate / MGI
- decreased circulating insulin level / MGI
- no phenotypic analysis / MGI
- decreased insulin secretion / MGI
- increased mean systemic arterial blood pressure / MGI
- increased spleen weight / MGI
- impaired glucose tolerance / MGI
- increased systemic arterial diastolic blood pressure / MGI
- increased systemic arterial systolic blood pressure / MGI
- impaired gastric peristalsis / MGI
- decreased susceptibility to weight gain / MGI
- increased lung compliance / MGI