MGI phenotypes (gene matching)
- no phenotypic analysis / MGI
C57BL/6N-Tmem45btm1.1Arte/Ieg
| Status | Available to order |
| EMMA ID | EM:05499 |
| Citation information | RRID:IMSR_EM:05499 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Tmem45btm1.1Arte/Ieg |
| Alternative name | TMEM45B KO cond |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Tmem45btm1.1 |
| Gene/Transgene symbol | Tmem45b |
Information from provider
| Provider | Helmholtz Zentrum Muenchen |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum Muenchen German Research Center for Environmental Health (GmbH) |
| Genetic information | Exons 3-5 have been flanked by loxP sites, as their genetic ablation should result in loss of function by deletion of most of the open reading frame and generation of a frameshift. The conditional targeted mutation has been obtained by in vivo, Flp recombinase-mediated removal of the neomycin selection marker. |
| Phenotypic information | TO BE PROVIDED |
| Breeding history | Targeting performed in C57BL/6N ES cells and confirmed by Southern blotting. Crossed to C57BL/6N-Tg(CAG-flpe)2Arte mice to obtain mutant founders with excised neo cassette. Maintained on C57BL/6N background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | not known |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C57BL/6NTac males, wild-type C57BL/6N females |
| Stage of embryos | 2-cell |