B6.129-Cdk11bGt(A20027)Wrst/Ieg

Status

Available to order

EMMA IDEM:05687
Citation informationRRID:IMSR_EM:05687 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6.129-Cdk11bGt(A20027)Wrst/Ieg
Alternative nameCdk11b (cell division cycle 2-like 1)
Strain typeGene-trap
Allele/Transgene symbolCdk11bGt(A20027)Wrst
Gene/Transgene symbolCdk11b

Information from provider

ProviderFranz Vauti
Provider affiliationCell- & Molecular Biology, Technical University of Braunschweig
Genetic informationCdk11b PT1betageo gene-trap.
Phenotypic informationEmbryonic lethal.
Breeding historyBackcrossed to C57BL/6 (N>7).
References
  • A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
  • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117
Homozygous fertilenot known
Homozygous viableno
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6J males

Disease and phenotype information

MGI phenotypes (gene matching)
  • decreased cell proliferation / MGI
  • thick epidermis / MGI
  • embryonic growth arrest / MGI
  • increased skin papilloma incidence / MGI
  • abnormal skin morphology / MGI
  • failure of blastocyst to hatch from the zona pellucida / MGI
  • embryonic lethality before implantation, complete penetrance / MGI
  • increased embryonic tissue cell apoptosis / MGI

Literature references

  • A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
  • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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