B6.129S2-Bptf^{Gt(A012C04)Wrst}/Ieg

Status	Available to order
EMMA ID	EM:05692
Citation information	RRID:IMSR_EM:05692 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	B6.129S2-Bptf^{Gt(A012C04)Wrst}/Ieg
Alternative name	Bptf (bromodomain PHD finger transcription factor)
Strain type	Gene-trap
Allele/Transgene symbol	Bptf^{Gt(A012C04)Wrst}
Gene/Transgene symbol	Bptf

Provider	Franz Vauti
Provider affiliation	Cell- & Molecular Biology, Technical University of Braunschweig
Genetic information	Bptf PT1betageo gene-trap.
Phenotypic information	Embryonic lethal.
Breeding history	Backcrossed into C57BL/6 (N>7).
References	Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development.;Goller Tobias, Vauti Franz, Ramasamy Suresh, Arnold Hans-Henning, ;2008;Molecular and cellular biology;28;6819-27; 18794365
Homozygous fertile	no
Homozygous viable	no
Homozygous matings required	no
Immunocompromised	not known

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany

Orphanet associated rare diseases, based on orthologous gene matching

IMPC phenotypes (gene matching)

MGI phenotypes (allele matching)

MGI phenotypes (gene matching)

decreased cell proliferation / MGI
abnormal ectoderm development / MGI
absent mesoderm / MGI
abnormal endoderm development / MGI
failure of primitive streak formation / MGI
decreased embryo size / MGI
abnormal proximal-distal axis patterning / MGI
embryonic growth arrest / MGI
abnormal developmental patterning / MGI
abnormal extraembryonic tissue morphology / MGI
abnormal primitive streak formation / MGI
small ectoplacental cone / MGI
abnormal chorion morphology / MGI
no phenotypic analysis / MGI
abnormal egg cylinder morphology / MGI
embryonic growth retardation / MGI
abnormal rostral-caudal axis patterning / MGI
absent chorion / MGI
embryonic lethality between implantation and somite formation, complete penetrance / MGI
embryonic lethality during organogenesis, complete penetrance / MGI
abnormal visceral endoderm morphology / MGI
thick embryonic epiblast / MGI
absent anterior visceral endoderm / MGI
absent distal visceral endoderm / MGI
abnormal primitive streak elongation / MGI

Transcriptional regulator BPTF/FAC1 is essential for trophoblast differentiation during early mouse development.;Goller Tobias, Vauti Franz, Ramasamy Suresh, Arnold Hans-Henning, ;2008;Molecular and cellular biology;28;6819-27; 18794365

Information from provider