B6.129S2-Hsd17b12Gt(A030E06)Wrst/Ieg

Status

Available to order

EMMA IDEM:05695
Citation informationRRID:IMSR_EM:05695 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

 
International strain nameB6.129S2-Hsd17b12Gt(A030E06)Wrst/Ieg
Alternative nameHsd17b12 (hydroxysteroid (17-beta) dehydrogenase 12)
Strain typeGene-trap
Allele/Transgene symbolHsd17b12Gt(A030E06)Wrst
Gene/Transgene symbolHsd17b12

Information from provider

ProviderFranz Vauti
Provider affiliationCell- & Molecular Biology, Technical University of Braunschweig
Genetic informationHsd17b12 Gt PT1betageo.
Phenotypic informationNot known; mouse line not yet characterized.
Breeding historyBackcrossed into C57BL/6 (N>7).
References
  • A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
  • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C57BL/6J males

Disease and phenotype information

MGI phenotypes (allele matching)
  • abnormal cell physiology / MGI
  • abnormal embryo development / MGI
  • decreased embryo size / MGI
  • abnormal visceral yolk sac morphology / MGI
  • absent vitelline blood vessels / MGI
  • abnormal extraembryonic tissue morphology / MGI
  • abnormal pluripotent precursor cell morphology / MGI
  • abnormal embryonic-extraembryonic boundary morphology / MGI
  • embryonic growth retardation / MGI
  • enlarged allantois / MGI
  • absent somites / MGI
  • absent chorion / MGI
  • embryonic lethality between somite formation and embryo turning, complete penetrance / MGI
  • decreased inner cell mass proliferation / MGI
MGI phenotypes (gene matching)
  • abnormal embryo development / MGI
  • decreased embryo size / MGI
  • abnormal visceral yolk sac morphology / MGI
  • absent vitelline blood vessels / MGI
  • abnormal extraembryonic tissue morphology / MGI
  • abnormal pluripotent precursor cell morphology / MGI
  • abnormal embryonic-extraembryonic boundary morphology / MGI
  • embryonic growth retardation / MGI
  • enlarged allantois / MGI
  • abnormal cell physiology / MGI
  • absent somites / MGI
  • absent chorion / MGI
  • embryonic lethality between somite formation and embryo turning, complete penetrance / MGI
  • decreased inner cell mass proliferation / MGI

Literature references

  • A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.;Hansen Jens, Floss Thomas, Van Sloun Petra, Füchtbauer Ernst-Martin, Vauti Franz, Arnold Hans-Hennig, Schnütgen Frank, Wurst Wolfgang, von Melchner Harald, Ruiz Patricia, ;2003;Proceedings of the National Academy of Sciences of the United States of America;100;9918-22; 12904583
  • Establishment of a gene-trap sequence tag library to generate mutant mice from embryonic stem cells.;Wiles M V, Vauti F, Otte J, Füchtbauer E M, Ruiz P, Füchtbauer A, Arnold H H, Lehrach H, Metz T, von Melchner H, Wurst W, ;2000;Nature genetics;24;13-4; 10615117

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

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