STOCK Dp(16App-Runx1)5Yah/Orl

Status	Available to order
EMMA ID	EM:05778
Citation information	RRID:IMSR_EM:05778 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	STOCK Dp(16App-Runx1)5Yah/Orl
Alternative name	Dp(16App-Runx1)5Yah
Strain type	Targeted Mutant Strains : Other targeted
Allele/Transgene symbol	Dp(16App-Runx1)5Yah
Gene/Transgene symbol	Dp(16App-Runx1)5Yah

Information from provider

Provider	Yann HERAULT
Provider affiliation	TAAM-CDTA UPS44, CNRS-TAAM – Typing and Archiving of Animal Models
Genetic information	This strain carries a duplication between App and Runx1 genes (MMU16).
Phenotypic information	No phenotype to date.
Breeding history	Male carrying a loxP site in Runx1 was mated to Hptr-Cre female. Female progeny carrying the loxP site in Runx1 and Hprt-Cre transgene was mated with a male carrying a loxP site in App gene. Female progeny carrying the 3 modifications was mated to C57BL/6 males to obtain the duplication.
References	Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis.;Pozner Amir, Lotem Joseph, Xiao Cuiying, Goldenberg Dalia, Brenner Ori, Negreanu Varda, Levanon Ditsa, Groner Yoram, ;2007;BMC developmental biology;7;84; 17626615 A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.;Tang Shih-Huey E, Silva Francisco J, Tsark Walter M K, Mann Jeffrey R, ;2002;Genesis (New York, N.Y. : 2000);32;199-202; 11892008
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France
Animals used for archiving	heterozygous C57BL/6J males, wild-type C57BL/6J females

Literature references

Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis.;Pozner Amir, Lotem Joseph, Xiao Cuiying, Goldenberg Dalia, Brenner Ori, Negreanu Varda, Levanon Ditsa, Groner Yoram, ;2007;BMC developmental biology;7;84; 17626615
A Cre/loxP-deleter transgenic line in mouse strain 129S1/SvImJ.;Tang Shih-Huey E, Silva Francisco J, Tsark Walter M K, Mann Jeffrey R, ;2002;Genesis (New York, N.Y. : 2000);32;199-202; 11892008

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen embryos. Delivered in 4 weeks (after paperwork in place). €1740^*
Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
For this strain no provider MTA is needed. Distribution is based on the EMMA conditions only.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.
Not found what you were looking for? Search here for other strains available from EMMA.