MGI phenotypes (allele matching)
STOCK Col4a1Svc/H
| Status | Available to order |
| EMMA ID | EM:00612 |
| Citation information | RRID:IMSR_EM:00612 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | STOCK Col4a1Svc/H |
| Alternative name | Svc |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Col4a1Svc |
| Gene/Transgene symbol | Col4a1 |
Information from provider
| Provider | Caroline Thaung |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Phenotypic information | Mutants are small and bruised at birth, and tend to remain small throughout life. Variable eye findings, the most consistent of which is a vacuolar cataract. Other eye findings include enlarged eyes, corneal opacity, iris-corneal adhesions, iris-lens adhesions, retinal vascular abnormalities. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
MGI phenotypes (gene matching)
- decreased hematocrit / MGI
- delayed kidney development / MGI
- weakness / MGI
- myopathy / MGI
- dystrophic muscle / MGI
- abnormal cerebral cortex morphology / MGI
- delaminated cerebral cortex / MGI
- abnormal hippocampus morphology / MGI
- decreased body weight / MGI
- decreased body size / MGI
- microphthalmia / MGI
- abnormal lens morphology / MGI
- cataract / MGI
- abnormal cornea morphology / MGI
- corneal opacity / MGI
- irregularly shaped pupil / MGI
- abnormal iris morphology / MGI
- abnormal retina morphology / MGI
- anemia / MGI
- abnormal blood vessel morphology / MGI
- polyuria / MGI
- kidney inflammation / MGI
- intracranial hemorrhage / MGI
- intracerebral hemorrhage / MGI
- reduced fertility / MGI
- infertility / MGI
- respiratory distress / MGI
- seizures / MGI
- premature death / MGI
- abnormal eye morphology / MGI
- abnormal kidney morphology / MGI
- abnormal kidney physiology / MGI
- abnormal brain morphology / MGI
- abnormal retinal vasculature morphology / MGI
- abnormal renal glomerular capsule morphology / MGI
- albuminuria / MGI
- decreased hemoglobin content / MGI
- decreased erythrocyte cell number / MGI
- increased urine microalbumin level / MGI
- decreased urine osmolality / MGI
- abnormal lens capsule morphology / MGI
- astrocytosis / MGI
- vitreal fibroplasia / MGI
- nervous system phenotype / MGI
- abnormal Reichert's membrane morphology / MGI
- abnormal kidney papilla morphology / MGI
- abnormal basement membrane morphology / MGI
- abnormal kidney collecting duct morphology / MGI
- abnormal proximal convoluted tubule morphology / MGI
- dilated kidney collecting duct / MGI
- hematuria / MGI
- abnormal renal glomerulus morphology / MGI
- abnormal podocyte morphology / MGI
- corneal vascularization / MGI
- increased blood urea nitrogen level / MGI
- brainstem hemorrhage / MGI
- abnormal retinal neuronal layer morphology / MGI
- eye hemorrhage / MGI
- optic nerve hypoplasia / MGI
- abnormal retinal ganglion cell morphology / MGI
- abnormal podocyte foot process morphology / MGI
- abnormal podocyte slit diaphragm morphology / MGI
- podocyte foot process effacement / MGI
- abnormal brain pia mater morphology / MGI
- dilated proximal convoluted tubules / MGI
- buphthalmos / MGI
- bruising / MGI
- decreased grip strength / MGI
- increased circulating creatine kinase level / MGI
- abnormal retinal blood vessel pattern / MGI
- abnormal retina inner limiting membrane morphology / MGI
- anterior subcapsular cataracts / MGI
- anterior polar cataracts / MGI
- sutural cataracts / MGI
- total cataracts / MGI
- postnatal lethality, incomplete penetrance / MGI
- perinatal lethality, incomplete penetrance / MGI
- prenatal lethality, complete penetrance / MGI
- embryonic lethality, complete penetrance / MGI
- lethality throughout fetal growth and development, complete penetrance / MGI
- prenatal lethality, incomplete penetrance / MGI
- abnormal parietal endoderm morphology / MGI
- abnormal glomerular mesangium morphology / MGI
- abnormal renal glomerulus basement membrane morphology / MGI
- enlarged brain ventricles / MGI
- renal cast / MGI
- erythrocyturia / MGI
- anterior iris synechia / MGI
- abnormal glomerular capsule parietal layer morphology / MGI
- increased glomerular capsule space / MGI
- parietal capsular epithelium metaplasia / MGI
- dilated glomerular capillary / MGI
- renal glomerulus cysts / MGI
- vacuolated lens / MGI
- abnormal kidney collecting duct epithelium morphology / MGI
- abnormal urine albumin level / MGI
- decreased collagen level / MGI