B6;FVB-Tg(Tagln-LacZ)4Zli/Orl
| Status | Available to order |
| EMMA ID | EM:00620 |
| Citation information | RRID:IMSR_EM:00620 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6;FVB-Tg(Tagln-LacZ)4Zli/Orl |
| Alternative name | SM22LacZ2126 |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Tagln-LacZ)4Zli |
| Gene/Transgene symbol | Tg(Tagln-LacZ)4Zli |
Information from provider
| Provider | Zhenlin LI |
| Provider affiliation | Université Pierre et Marie Curie |
| Genetic information | The construct consist of a promoter fragment of the Tagln (SM22-alpha) murine gene, covering the region -2126 to +65 relative to the transcriptional start, and an E.coli lacZ reporter gene with a nuclear localization signal. The expression pattern is restricted to embryonic heart, myotomes and arterial smooth muscles. In the adult, expression is restricted to arterial smooth muscle cells and to some cardiomyocytes of the left ventricle. |
| Breeding history | Founders (born in 1994) were bred with C57BL/6. |
| References |
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Information from EMMA
| Archiving centre | CNRS-TAAM – Typing and Archiving of Animal Models, Orléans, France |
Literature references
- The SM 22 promoter directs tissue-specific expression in arterial but not in venous or visceral smooth muscle cells in transgenic mice.;Moessler H, Mericskay M, Li Z, Nagl S, Paulin D, Small J V, ;1996;Development (Cambridge, England);122;2415-25; 8756287