MGI phenotypes (allele matching)
- striated fur / MGI
C3H;C-Tal44H/H
| Status | Available to order |
| EMMA ID | EM:00641 |
| Citation information | RRID:IMSR_EM:00641 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3H;C-Tal44H/H |
| Alternative name | Ta<44H> |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Tal44H |
| Gene/Transgene symbol | Eda |
Information from provider
| Provider | Neil Dear |
| Provider affiliation | MRC Mammalian Genetics Unit |
| Phenotypic information | The tabby (Ta) mutation (anhidrotic ectodermal dysplasia) is a mouse model for X-linked hypohidrotic ectodermal dysplasia. This is a congenital disorder resulting in abnormal tooth, hair and sweat gland development. Ta44H: Ta-like phenotype, i.e. striped heterozygous females, hemizygous males have no guard hairs, bald tails often with kink near tip, very little hair behind ears. Limited breeding data suggest good viability of both heterozygous females and hemizygous males. Penetrance of mutation would also appear to be good. |
| References | None available |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- X-linked hypohidrotic ectodermal dysplasia / Orphanet_181
- Oligodontia / Orphanet_99798
MGI phenotypes (gene matching)
- abnormal coat/ hair morphology / MGI
- irregular coat pigmentation / MGI
- increased curvature of hairs / MGI
- sparse hair / MGI
- focal hair loss / MGI
- kinked tail / MGI
- thin skin / MGI
- thin epidermis / MGI
- abnormal coat appearance / MGI
- female infertility / MGI
- abnormal hair growth / MGI
- abnormal hair texture / MGI
- abnormal coat/hair pigmentation / MGI
- abnormal skin pigmentation / MGI
- abnormal tail morphology / MGI
- abnormal nose morphology / MGI
- abnormal nasal cavity morphology / MGI
- abnormal hair follicle development / MGI
- abnormal hair follicle melanocyte morphology / MGI
- narrow eye opening / MGI
- absent guard hair / MGI
- absent zigzag hairs / MGI
- absent hair follicle pheomelanosome pheomelanin / MGI
- decreased zigzag hair amount / MGI
- abnormal vibrissa number / MGI
- abnormal palatal rugae morphology / MGI
- striated fur / MGI
- transverse fur striping / MGI
- hairless tail / MGI
- abnormal tail ring morphology / MGI
- abnormal nasal gland morphology / MGI
- abnormal lateral nasal gland morphology / MGI