C3HeB/FeJ-Scg3^m1Mhda/Ieg

Status	Available to order
EMMA ID	EM:07466
Citation information	RRID:IMSR_EM:07466 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	C3HeB/FeJ-Scg3^m1Mhda/Ieg
Alternative name	C3HeB/FeJ-Scg3N180KMhdA/ieg
Strain type	Induced Mutant Strains : Chemically-induced
Allele/Transgene symbol	Scg3^m1Mhda
Gene/Transgene symbol	Scg3

Information from provider

Provider	Sibylle Sabrautzki
Provider affiliation	Institute of Experimental Genetics, Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH)
Genetic information	Missense mutation in exon 5 of Scg3 c.540T->G, p.N180K.
Phenotypic information	Heterozygous mice with no overt phenotype, homozygous mice not analyzed.
Breeding history	More than 5 generations on pure C3HeB/FeJ background.
References	None available
Homozygous fertile	not known
Homozygous viable	not known
Homozygous matings required	no
Immunocompromised	not known

Information from EMMA

Archiving centre	Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archiving	heterozygous C3H males

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

Gamma-sarcoglycan-related limb-girdle muscular dystrophy R5 / Orphanet_353

IMPC phenotypes (gene matching)

hyperactivity / IMPC
increased vertical activity / IMPC

MGI phenotypes (allele matching)

no phenotypic analysis / MGI

MGI phenotypes (gene matching)

no abnormal phenotype detected / MGI
abnormal pancreas physiology / MGI
decreased circulating insulin level / MGI
no phenotypic analysis / MGI
impaired glucose tolerance / MGI
homeostasis/metabolism phenotype / MGI
behavior/neurological phenotype / MGI
reproductive system phenotype / MGI
abnormal pituitary gland physiology / MGI
increased susceptibility to diet-induced obesity / MGI
mortality/aging / MGI

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

The information provided on this page is, to the best of EMMA’s knowledge, based on data supplied by the original provider. End users are responsible for reviewing these details and for validating the strain and its suitability for their experimental use.
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C3HeB/FeJ-Scg3m1Mhda/Ieg