| Status | Available to order |
| EMMA ID | EM:07575 |
| Citation information | RRID:IMSR_EM:07575 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6NCrl-Dicer1em3Psv/Ph |
| Alternative name | DcrMTdel |
| Strain type | Endonuclease-mediated |
| Allele/Transgene symbol | Dicer1em3Psv |
| Gene/Transgene symbol | Dicer1 |
| Provider | Petr Svoboda |
| Provider affiliation | Dep. of Epigenetic Regulations, Institute of Molecular Genetics, v.v.i |
| Genetic information | TALEN-mediated deletion of MT-C (mouse transcript, type C) element in intron 6 of Dicer1 gene. |
| Phenotypic information | Sterility of homozygous females due to defects in oocyte maturation. Males and heterozygous females are fertile and without apparent phenotype. |
| Breeding history | Positive F0 mice were crossed with C57BL/6NCrl mice to get F1 generation. Transmitting F1 mice were intercrossed to obtain mice with all genotypes. |
| References |
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| Homozygous fertile | no |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
| Animals used for archiving | heterozygous C57BL/6N males |
Orphanet associated rare diseases, based on orthologous gene matching
