MGI phenotypes (gene matching)
- no abnormal phenotype detected / MGI
B6.Cg-Tg(Hspa1b-mPlum)AAmpla/Cnbc
| Status | Available to order |
| EMMA ID | EM:07593 |
| Citation information | RRID:IMSR_EM:07593 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Tg(Hspa1b-mPlum)AAmpla/Cnbc |
| Alternative name | C57BL/6 Jclr;B6CBA-Tg(hsp70-mPlum)/A-Ampla |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Hspa1b-mPlum)AAmpla |
| Gene/Transgene symbol | Tg(Hspa1b-mPlum)AAmpla |
Information from provider
| Provider | Anna M. Planas |
| Provider affiliation | Cerebral Ischemia & neurodegeneration, IIBB-CSIC/IDIBAPS |
| Genetic information | Genome contains the Hsp70-mPlum reporter plasmid. |
| Phenotypic information | Tissues where hsp70 is activated produce the far-red fluorescent protein mPlum that can be detected by fluorescence reflectance imaging and intravital confocal microscopy. |
| Breeding history | The founder transgenic mouse was initially produced in a (C57BL/6J x CBA/J)F2 background. The model has been backcrossed to C57BL/6J CRL for 11 generations. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | CNB-CSIC, Centro Nacional de Biotecnologia, Madrid, Spain |
| Animals used for archiving | heterozygous males, wild-type females |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- In vivo imaging of induction of heat-shock protein-70 gene expression with fluorescence reflectance imaging and intravital confocal microscopy following brain ischaemia in reporter mice.;de la Rosa Xavier, Santalucía Tomàs, Fortin Pierre-Yves, Purroy Jesús, Calvo Maria, Salas-Perdomo Angélica, Justicia Carles, Couillaud Franck, Planas Anna M, ;2013;European journal of nuclear medicine and molecular imaging;40;426-38; 23135322