IMPC phenotypes (gene matching)
B6.Cg-Zbed6tm1.2Sson/Kctt
| Status | Available to order |
| EMMA ID | EM:08120 |
| Citation information | RRID:IMSR_EM:08120 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.Cg-Zbed6tm1.2Sson/Kctt |
| Alternative name | Zbed6-/- |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Zbed6tm1.2Sson |
| Gene/Transgene symbol | Zbed6 |
Information from provider
| Provider | Leif Andersson |
| Provider affiliation | Department of Medical Biochemistry and Microbiology, Uppsala University |
| Genetic information | Knock-out model for the Zbed6 gene. |
| Phenotypic information | Homozygous:Indication of higher weight in homozygous KO mice compared to heterozygotes and wild-type.Heterozygous:Indication of higher weight in heterozygous mice compared to wild-type. |
| Breeding history | Line was generated in C57BL/6 ES cells (Bruce4). |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | homozygous C57BL/6J males, wild-type C57BL/6J females |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals.;Younis Shady, Schönke Milena, Massart Julie, Hjortebjerg Rikke, Sundström Elisabeth, Gustafson Ulla, Björnholm Marie, Krook Anna, Frystyk Jan, Zierath Juleen R, Andersson Leif, ;2018;Proceedings of the National Academy of Sciences of the United States of America;115;E2048-E2057; 29440408