- decreased circulating serum albumin level / IMPC
129P2(Cg)-Galr2tm1.1Wyn/H
| Status | Available to order |
| EMMA ID | EM:08193 |
| Citation information | RRID:IMSR_EM:08193 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | 129P2(Cg)-Galr2tm1.1Wyn/H |
| Alternative name | GalR2- hrGFP tagged mice |
| Strain type | Targeted Mutant Strains : Knock-in |
| Allele/Transgene symbol | Galr2tm1.1Wyn |
| Gene/Transgene symbol | Galr2 |
Information from provider
| Provider | David Wynick |
| Provider affiliation | Medical Sciences Bristol, Research NBT and UHBristol |
| Genetic information | hrGFP tag of Galr2 gene |
| Phenotypic information | Homozygous:No phenotypeHeterozygous:No phenotype |
| Breeding history | E14 ES cell line. Crossed to flp deleters to remove neo cassette. Maintained on pure 129/OlaHsd. Newly generated. |
| References |
|
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
IMPC phenotypes (gene matching)
MGI phenotypes (gene matching)
- abnormal L5 dorsal root ganglion morphology / MGI
- increased thermal nociceptive threshold / MGI
- decreased vertical activity / MGI
- abnormal excitatory postsynaptic potential / MGI
- increased T cell number / MGI
- decreased B cell number / MGI
- behavior/neurological phenotype / MGI
- impaired conditioned place preference behavior / MGI
Literature references
- The generation of knock-in mice expressing fluorescently tagged galanin receptors 1 and 2.;Kerr Niall, Holmes Fiona E, Hobson Sally-Ann, Vanderplank Penny, Leard Alan, Balthasar Nina, Wynick David, ;2015;Molecular and cellular neurosciences;68;258-71; 26292267
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