MGI phenotypes (allele matching)
- no phenotypic analysis / MGI
C57BL/6-Tg(Hist1h1t-sb100X)8689Izsv/Ph
| Status | Available to order |
| EMMA ID | EM:08254 |
| Citation information | RRID:IMSR_EM:08254 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6-Tg(Hist1h1t-sb100X)8689Izsv/Ph |
| Alternative name | C57 BL6 mice |
| Strain type | Transgenic Strains |
| Allele/Transgene symbol | Tg(Hist1h1t-sb100X)8689Izsv |
| Gene/Transgene symbol | Tg(Hist1h1t-sb100X)8689Izsv |
Information from provider
| Provider | Zsuzsanna Izsvak |
| Provider affiliation | Mobile DNA, Max Delbruk Centre |
| Genetic information | Transgenic for Sleeping Beauty hyperactive transposase SB100X which is expressed in the male germ line. The transposase expression is driven by the Hist1h1t (H1t) promoter which is expressed during early spermatogenesis. |
| Phenotypic information | Homozygous:Expected to be normal. Producer did not try to generate homozygous mice but theoretically the transposase transgene should not be harmful to the animal.Heterozygous:Normal |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Institute of Molecular Genetics, Prague, Czech Republic |
Disease and phenotype information
Literature references
- Retrotransposition creates sloping shores: a graded influence of hypomethylated CpG islands on flanking CpG sites.;Grandi Fiorella C, Rosser James M, Newkirk Simon J, Yin Jun, Jiang Xiaoling, Xing Zhuo, Whitmore Leanne, Bashir Sanum, Ivics Zoltán, Izsvák Zsuzsanna, Ye Ping, Yu Y Eugene, An Wenfeng, ;2015;Genome research;25;1135-46; 25995269