IMPC phenotypes (gene matching)
C57BL/6N-Cnr2tm1Ics/Ics
| Status | Available to order |
| EMMA ID | EM:08287 |
| Citation information | RRID:IMSR_EM:08287 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C57BL/6N-Cnr2tm1Ics/Ics |
| Alternative name | CB2 flox |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Cnr2tm1Ics |
| Gene/Transgene symbol | Cnr2 |
Information from provider
| Provider | Sophie LOTERSZTAJN |
| Provider affiliation | Inserm UMR 1149, Université Paris Diderot |
| Genetic information | Insertion of loxP sites in the cannabinoid receptor 2 (Cnr2) gene. C57BL/6N mouse embryonic stem (ES) cells. |
| Phenotypic information | Homozygous:None.Heterozygous:None |
| Breeding history | C57BL/6N background. |
| References |
|
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | ICS, Institut Clinique de la Souris, Illkirch-Graffenstaden, France |
| Animals used for archiving | heterozygous C57BL/6NCrl males, wild-type C57BL/6NCrl females |
| Stage of embryos | 2-cell |
Disease and phenotype information
Literature references
- The Cannabinoid Receptor 2 Protects Against Alcoholic Liver Disease Via a Macrophage Autophagy-Dependent Pathway.;Denaës Timothé, Lodder Jasper, Chobert Marie-Noële, Ruiz Isaac, Pawlotsky Jean-Michel, Lotersztajn Sophie, Teixeira-Clerc Fatima, ;2016;Scientific reports;6;28806; 27346657