STOCK Tg(TNFRSF1B)1334Gkl/Flmg

Status	Available to order
EMMA ID	EM:08377
Citation information	RRID:IMSR_EM:08377 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.
International strain name	STOCK Tg(TNFRSF1B)1334Gkl/Flmg
Alternative name	CBA.B6-Tg(TNFRSF1B)1334Gkl/Flmg
Strain type	Transgenic Strains
Allele/Transgene symbol	Tg(TNFRSF1B)1334Gkl
Gene/Transgene symbol	Tg(TNFRSF1B)1334Gkl

Information from provider

Provider	George Kollias
Provider affiliation	BSRC Al. Fleming
Genetic information	Tg1334 mice contain as transgene a 70 kb DNA fragment comprising the entire human TNFR2 genomic sequence. These mice express human TNFR2 in a physiological relevant pattern and grow normally without displaying any pathological changes.
Phenotypic information	Homozygous: No overt pathology Heterozygous: No overt pathology
References	A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.;Douni E, Kollias G, ;1998;The Journal of experimental medicine;188;1343-52; 9763613
Homozygous fertile	yes
Homozygous viable	yes
Homozygous matings required	no
Immunocompromised	no

Information from EMMA

Archiving centre	B.S.R.C. Alexander Fleming, Vari, Greece
Animals used for archiving	heterozygous CBA x C57BL/6 males

Literature references

A critical role of the p75 tumor necrosis factor receptor (p75TNF-R) in organ inflammation independent of TNF, lymphotoxin alpha, or the p55TNF-R.;Douni E, Kollias G, ;1998;The Journal of experimental medicine;188;1343-52; 9763613

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Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740^*
Rederivation of mice from frozen stock, delivery time available upon request . €3880^*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

^* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

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