C3HeB/FeJ-Nkx6-1m1Mhda/Ieg

Status

Available to order

EMMA IDEM:08443
Citation informationRRID:IMSR_EM:08443 

Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information.

International strain nameC3HeB/FeJ-Nkx6-1m1Mhda/Ieg
Alternative nameC3HeB/FeJ-Nkx6D325NMhda
Strain typeInduced Mutant Strains : Chemically-induced
Allele/Transgene symbolNkx6-1m1Mhda
Gene/Transgene symbolNkx6-1

Information from provider

ProviderMartin Hrabe de Angelis
Provider affiliationInstitute of Experimental Genetics, Helmholtz Zentrum München
Genetic informationMissense mutation c.973C>T, p.Asp325Asn.
Phenotypic informationHomozygous:
No homozygous mice obtained.

Heterozygous:
Not obvious.
Breeding historyGenerated and maintained on pure C3HeB/FeJ background.
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requiredno
Immunocompromisedno

Information from EMMA

Archiving centreHelmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany
Animals used for archivingheterozygous C3H males

Disease and phenotype information

MGI phenotypes (gene matching)
  • forelimb paralysis / MGI
  • decreased motor neuron number / MGI
  • abnormal motor capabilities/coordination/movement / MGI
  • abnormal neuron specification / MGI
  • no phenotypic analysis / MGI
  • decreased insulin secretion / MGI
  • decreased pancreatic beta cell number / MGI
  • abnormal spinal cord interneuron morphology / MGI
  • small pancreatic islets / MGI
  • neonatal lethality, complete penetrance / MGI

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Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable).

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
Distribution of this strain is subject to a provider MTA. Both signing of the MTA and submission of the online EMMA Mutant Request Form are required before material can be shipped.

EMMA conditions
Legally binding conditions for the transfer

Right strain for your research?

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