- forelimb paralysis / MGI
- decreased motor neuron number / MGI
- abnormal motor capabilities/coordination/movement / MGI
- abnormal neuron specification / MGI
- no phenotypic analysis / MGI
- decreased insulin secretion / MGI
- decreased pancreatic beta cell number / MGI
- abnormal spinal cord interneuron morphology / MGI
- small pancreatic islets / MGI
- neonatal lethality, complete penetrance / MGI
C3HeB/FeJ-Nkx6-1m1Mhda/Ieg
| Status | Available to order |
| EMMA ID | EM:08443 |
| Citation information | RRID:IMSR_EM:08443 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Nkx6-1m1Mhda/Ieg |
| Alternative name | C3HeB/FeJ-Nkx6D325NMhda |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Nkx6-1m1Mhda |
| Gene/Transgene symbol | Nkx6-1 |
Information from provider
| Provider | Martin Hrabe de Angelis |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum München |
| Genetic information | Missense mutation c.973C>T, p.Asp325Asn. |
| Phenotypic information | Homozygous:No homozygous mice obtained.Heterozygous:Not obvious. |
| Breeding history | Generated and maintained on pure C3HeB/FeJ background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C3H males |
Disease and phenotype information
MGI phenotypes (gene matching)
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