IMPC phenotypes (gene matching)
C3HeB/FeJ-Arhgap25m1Mhda/Ieg
| Status | Available to order |
| EMMA ID | EM:08900 |
| Citation information | RRID:IMSR_EM:08900 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Arhgap25m1Mhda/Ieg |
| Alternative name | C3HeB/FeJ-Arhgap25 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Arhgap25m1Mhda |
| Gene/Transgene symbol | Arhgap25 |
Information from provider
| Provider | Martin Hrabe de Angelis |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum München |
| Genetic information | Nonsense point mutation of Arhgap25 c.847G->A, p.R257X |
| Phenotypic information | Homozygous:No obvious phenotype observed.Heterozygous:No obvious phenotype observed. |
| Breeding history | Pure C3HeB/FeJ background, homozygous intercrossed; internal lab code Arhgap-01. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C3H males |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased neutrophil cell number / MGI
- decreased body weight / MGI
- abnormal retina morphology / MGI
- abnormal neutrophil physiology / MGI
- increased acute inflammation / MGI
- abnormal retinal pigmentation / MGI
- hematopoietic system phenotype / MGI
- increased mean corpuscular hemoglobin / MGI
- abnormal cellular extravasation / MGI
- enhanced leukocyte migration / MGI
- enhanced leukocyte tethering or rolling / MGI