- polycystic kidney / IMPC
- abnormal skin morphology / IMPC
- increased heart weight / IMPC
- increased red blood cell distribution width / IMPC
- preweaning lethality, complete penetrance / IMPC
- enlarged urinary bladder / IMPC
- prenatal lethality prior to heart atrial septation / IMPC
- embryonic lethality prior to organogenesis / IMPC
- abnormal sternum morphology / IMPC
- increased spleen weight / IMPC
C3HeB/FeJ-Nelfam1Mhda/Ieg
| Status | Available to order |
| EMMA ID | EM:08915 |
| Citation information | RRID:IMSR_EM:08915 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Nelfam1Mhda/Ieg |
| Alternative name | C3HeB/FeJ-Whsc2I79NMhda |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Nelfam1Mhda |
| Gene/Transgene symbol | Nelfa |
Information from provider
| Provider | Martin Hrabe de Angelis |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum München |
| Genetic information | Missense point mutation in exon 2 of Whsc2 (Nelfa) c.236T->A, p.I79N; PROVEAN result -6.2 = deleterious |
| Phenotypic information | Homozygous:Not analyzed.Heterozygous:No obvious phenotype observed. |
| Breeding history | Pure C3HeB/FeJ background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C3H males |
Disease and phenotype information
IMPC phenotypes (gene matching)
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