IMPC phenotypes (gene matching)
- head bobbing / IMPC
C3HeB/FeJ-Sipa1Mhdaate003/Ieg
| Status | Available to order |
| EMMA ID | EM:09146 |
| Citation information | RRID:IMSR_EM:09146 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Sipa1Mhdaate003/Ieg |
| Alternative name | Sipa1S971AMhda; internal lab code ATE003 |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Sipa1Mhdaate003 |
| Gene/Transgene symbol | Sipa1 |
Information from provider
| Provider | Martin Hrabe de Angelis |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum München |
| Genetic information | dominant ENU mutagenesis derived mouse line; exon 17 c.2911T>G, p.S971A |
| Phenotypic information | Homozygous:white incisorsHeterozygous:white incisors |
| References | None available |
| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | not known |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C3H males |
Disease and phenotype information
MGI phenotypes (gene matching)
- increased leukocyte cell number / MGI
- extramedullary hematopoiesis / MGI
- increased bone marrow cell number / MGI
- increased granulocyte number / MGI
- enlarged spleen / MGI
- spleen hyperplasia / MGI
- anemia / MGI
- abnormal definitive hematopoiesis / MGI
- abnormal bone marrow cell morphology/development / MGI
- decreased erythrocyte cell number / MGI
- increased hematopoietic stem cell number / MGI
- pancytopenia / MGI
- increased chronic myelocytic leukemia incidence / MGI