B6.129-Prdm11tm1Ahl/Kctt
| Status | Available to order |
| EMMA ID | EM:09214 |
| Citation information | RRID:IMSR_EM:09214 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129-Prdm11tm1Ahl/Kctt |
| Alternative name | Prdm11 Neo |
| Strain type | Targeted Mutant Strains : Conditional mutation |
| Allele/Transgene symbol | Prdm11tm1Ahl |
| Gene/Transgene symbol | Prdm11 |
Information from provider
| Provider | Anders H. Lund |
| Provider affiliation | Lund Group, Biotech Research and Innovation Centre, University of Copenhagen |
| Genetic information | Generation of Prdm11 Neo mice was done by gene targeting. 129 R1 ES cell clones containing a neomycin resistance coding sequence (neoR) flanked by frt sites integrated in intron1 and presenting loxP sites in intron 1 (before the cassette) and in intron 4, Prdm11 gene were generated. Chimeras were further characterized for germ-line transfer of the targeted allele, leading to Prdm11 neo/+ mice. |
| Phenotypic information | Homozygous:none detectedHeterozygous:none detected |
| Breeding history | Only backcrosses with C57BL/6J. |
| References |
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| Homozygous fertile | not known |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Karolinska Institutet, Stockholm, Sweden |
| Animals used for archiving | heterozygous C57BL/6J males, wild-type females |
| Stage of embryos | 2-cell |
Literature references
- PRDM11 is dispensable for the maintenance and function of hematopoietic stem and progenitor cells.;Thoren Lina A, Fog Cathrine K, Jensen Klaus T, Buza-Vidas Natalija, Côme Christophe, Lund Anders H, Porse Bo T, ;2013;Stem cell research;11;1129-36; 23978475