| Status | Available to order |
| EMMA ID | EM:09858 |
| Citation information | RRID:IMSR_EM:09858 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | B6.129S2-Parp2tm1Jmdm/Biat |
| Alternative name | PARP2 |
| Strain type | Targeted Mutant Strains : Knock-out |
| Allele/Transgene symbol | Parp2tm1Jmdm |
| Gene/Transgene symbol | Parp2 |
| Provider | Gilbert de Murcia |
| Provider affiliation | UMR7242, CNRS |
| Additional owner | Francoise Dantzer and Valérie Schreiber, CNRS-UMR7242, Illkirch, France |
| Genetic information | The Parp2 gene has been inactivated by homologous recombination in ES cells from the 129/Pas mouse line by inserting the PGK-hygromycin cassette in exon 9. |
| Phenotypic information | Homozygous:The mice display sensitivity to DNA damaging agents (IR, MNU). The mice are viable and fertile. Male hypofertility has been observed in the pure C57BL/6 background.Heterozygous:No phenotype for the heterozygotes. |
| References |
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| Homozygous fertile | yes |
| Homozygous viable | yes |
| Homozygous matings required | no |
| Immunocompromised | no |
| Archiving centre | University of Veterinary Medicine, Vienna, Austria |
| Breeding at archiving centre | Parp1 (EMMA ID EM:09855) and Parp2 (EMMA ID EM:09858) strains have been imported as refrig. epid.; SF males were produced out of these, sperm frozen and quality-controlled. Therefore prolonged archiving period. |
