IMPC phenotypes (gene matching)
C3HeB/FeJ-Polr3bm1Mhda/Ieg
| Status | Available to order |
| EMMA ID | EM:09871 |
| Citation information | RRID:IMSR_EM:09871 Research Resource Identifiers (RRID) are persistent unique ID numbers assigned to help researchers cite key resources (e.g. antibodies, model organisms and software projects) in the biomedical literature to improve transparency and reproducibility in research. See https://www.rrids.org/ for more information. |
| International strain name | C3HeB/FeJ-Polr3bm1Mhda/Ieg |
| Alternative name | C3HeB/FeJ-Polr3bF459LMhda |
| Strain type | Induced Mutant Strains : Chemically-induced |
| Allele/Transgene symbol | Polr3bm1Mhda |
| Gene/Transgene symbol | Polr3b |
Information from provider
| Provider | Martin Hrabe de Angelis |
| Provider affiliation | Institute of Experimental Genetics, Helmholtz Zentrum München |
| Genetic information | Dominant point mutation in exon 14 of Polr3b, c.1375T>C, p.Phe459Leu; internal lab code WBS018. |
| Phenotypic information | Homozygous:not analyzedHeterozygous:heterozygous white belly spot; short body, short skull, short tail |
| Breeding history | Pure C3HeB/FeJ background. |
| References | None available |
| Homozygous fertile | not known |
| Homozygous viable | not known |
| Homozygous matings required | no |
| Immunocompromised | no |
Information from EMMA
| Archiving centre | Helmholtz Zentrum Muenchen - German Research Center for Environmental Health (GmbH), Oberschleißheim, Germany |
| Animals used for archiving | heterozygous C3H males |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Hypomyelination-hypogonadotropic hypogonadism-hypodontia syndrome / Orphanet_88637
- Endosteal sclerosis-cerebellar hypoplasia syndrome / Orphanet_85186