C3H101H-Tc/H

Status

Available to order

EMMA IDEM:02201
Citation informationRRID:IMSR_EM:02201 

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International strain nameC3H101H-Tc/H
Alternative nameCurtailed
Strain typeInduced Mutant Strains : Radiation-induced
Allele/Transgene symbolTc
Gene/Transgene symbolT

Information from provider

ProviderAnthony Searle
Provider affiliationMedical Research Council (Retired)
Genetic informationFather received 2Gy X-rays as a fetus.
Phenotypic informationTc/+ and Tc/th7 mice are tailless. Homozygous lethal.
References
  • Curtailed, a new dominant T-allele in the house mouse.;Searle A G, ;1966;Genetical research;7;86-95; 5906493

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

MGI phenotypes (allele matching)
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • rib fusion / MGI
  • decreased presacral vertebrae number / MGI
  • short tail / MGI
  • postnatal lethality / MGI
  • abnormal tail morphology / MGI
  • abnormal cervical vertebrae morphology / MGI
  • absent tail / MGI
  • abnormal cervical atlas morphology / MGI
  • vertebral fusion / MGI
  • fusion of vertebral arches / MGI
  • cervical vertebral fusion / MGI
  • thoracic vertebral fusion / MGI
  • abnormal odontoid process morphology / MGI
  • short ribs / MGI
  • abnormal vertebral arch development / MGI
  • abnormal nucleus pulposus morphology / MGI
  • abnormal bone ossification / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • absent vertebrae / MGI
  • abnormal spinal cord morphology / MGI
  • abnormal neural tube morphology / MGI
  • abnormal tail bud morphology / MGI
  • split notochord / MGI
  • spina bifida occulta / MGI
  • distended pericardium / MGI
  • abnormal embryo development / MGI
  • abnormal allantois morphology / MGI
  • kinked neural tube / MGI
  • caudal body truncation / MGI
  • abnormal neural fold formation / MGI
  • abnormal limb bud morphology / MGI
  • absent somites / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI
  • absent tail bud / MGI
  • absent forelimb buds / MGI
  • absent hindlimb buds / MGI
MGI phenotypes (gene matching)
  • absent vertebrae / MGI
  • rib fusion / MGI
  • abnormal heart looping / MGI
  • abnormal heart tube morphology / MGI
  • distended pericardium / MGI
  • increased mast cell number / MGI
  • decreased presacral vertebrae number / MGI
  • kinked tail / MGI
  • short tail / MGI
  • abnormal spleen morphology / MGI
  • abnormal thymus morphology / MGI
  • thymus cortex hypoplasia / MGI
  • open neural tube / MGI
  • absent notochord / MGI
  • abnormal spinal cord morphology / MGI
  • seminiferous tubule degeneration / MGI
  • abnormal spermatogenesis / MGI
  • abnormal epidermal layer morphology / MGI
  • decreased body weight / MGI
  • decreased body size / MGI
  • decreased caudal vertebrae number / MGI
  • abnormal embryo development / MGI
  • abnormal axial mesoderm / MGI
  • abnormal somite development / MGI
  • incomplete somite formation / MGI
  • decreased embryo size / MGI
  • incomplete embryo turning / MGI
  • abnormal placenta development / MGI
  • abnormal allantois morphology / MGI
  • embryonic growth arrest / MGI
  • edema / MGI
  • hemorrhage / MGI
  • reduced fertility / MGI
  • reduced male fertility / MGI
  • male infertility / MGI
  • decreased litter size / MGI
  • prenatal lethality / MGI
  • perinatal lethality / MGI
  • postnatal lethality / MGI
  • abnormal embryonic tissue morphology / MGI
  • abnormal tail morphology / MGI
  • abnormal neural tube morphology / MGI
  • no abnormal phenotype detected / MGI
  • abnormal primitive streak formation / MGI
  • abnormal thymus cortex morphology / MGI
  • increased susceptibility to infection / MGI
  • vestigial tail / MGI
  • abnormal notochord morphology / MGI
  • abnormal tail bud morphology / MGI
  • abnormal cervical vertebrae morphology / MGI
  • curly tail / MGI
  • absent allantois / MGI
  • kinked neural tube / MGI
  • absent tail / MGI
  • abnormal nervous system development / MGI
  • abnormal Reichert's membrane morphology / MGI
  • embryonic growth retardation / MGI
  • disorganized embryonic tissue / MGI
  • caudal body truncation / MGI
  • transmission ratio distortion / MGI
  • failure of heart looping / MGI
  • abnormal pelvic girdle bone morphology / MGI
  • abnormal cervical atlas morphology / MGI
  • vertebral fusion / MGI
  • fusion of vertebral arches / MGI
  • cervical vertebral fusion / MGI
  • thoracic vertebral fusion / MGI
  • abnormal odontoid process morphology / MGI
  • short ribs / MGI
  • notochord degeneration / MGI
  • split notochord / MGI
  • abnormal dorsal aorta morphology / MGI
  • abnormal neural fold formation / MGI
  • abnormal trophectoderm morphology / MGI
  • abnormal ectoplacental cone morphology / MGI
  • abnormal vertebral arch development / MGI
  • hemopericardium / MGI
  • spina bifida occulta / MGI
  • limbs/digits/tail phenotype / MGI
  • reproductive system phenotype / MGI
  • teratozoospermia / MGI
  • abnormal limb bud morphology / MGI
  • abnormal tail development / MGI
  • absent somites / MGI
  • abnormal nucleus pulposus morphology / MGI
  • increased megakaryocyte cell number / MGI
  • abnormal bone ossification / MGI
  • arrest of spermiogenesis / MGI
  • decreased spleen white pulp amount / MGI
  • embryonic lethality / MGI
  • bleb / MGI
  • early reproductive senescence / MGI
  • absent anus / MGI
  • abnormal sperm head morphology / MGI
  • abnormal sperm nucleus morphology / MGI
  • abnormal manchette morphology / MGI
  • mortality/aging / MGI
  • postnatal lethality, incomplete penetrance / MGI
  • neonatal lethality, complete penetrance / MGI
  • neonatal lethality, incomplete penetrance / MGI
  • perinatal lethality, incomplete penetrance / MGI
  • prenatal lethality, complete penetrance / MGI
  • embryonic lethality, complete penetrance / MGI
  • embryonic lethality between implantation and placentation, complete penetrance / MGI
  • embryonic lethality between implantation and somite formation, complete penetrance / MGI
  • embryonic lethality between somite formation and embryo turning, complete penetrance / MGI
  • embryonic lethality during organogenesis, complete penetrance / MGI
  • preweaning lethality, complete penetrance / MGI
  • embryonic lethality during organogenesis, incomplete penetrance / MGI
  • preweaning lethality, incomplete penetrance / MGI
  • decreased embryonic epiblast cell proliferation / MGI
  • lethality, complete penetrance / MGI
  • abnormal head shape / MGI
  • absent tail bud / MGI
  • delayed heart development / MGI
  • abnormal pericardial cavity morphology / MGI
  • decreased ventral ectodermal ridge size / MGI
  • abnormal forelimb bud morphology / MGI
  • absent forelimb buds / MGI
  • absent hindlimb buds / MGI

Literature references

  • Curtailed, a new dominant T-allele in the house mouse.;Searle A G, ;1966;Genetical research;7;86-95; 5906493

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