B6.129-Lta/Tnftm1Fda/Orl
Status | Available to order |
EMMA ID | EM:01780 |
International strain name | B6.129-Lta/Tnftm1Fda/Orl |
Alternative name | tnf, lt KO (C57BL/6) |
Strain type | Targeted Mutant Strains : Knock-out |
Allele/Transgene symbol | Lta/Tnftm1Fda, |
Gene/Transgene symbol | Lta |
Information from provider
Provider | Gilles Marchal |
Provider affiliation | Institut Pasteur |
Phenotypic information | Small size of the progeny; sometimes it is necessary to use foster mothers. |
Breeding history | The strain was backcrossed to C57BL/6 for 20 generations. It has been inbred since the 20th generation. |
References |
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Information from EMMA
Archiving centre | Institut de Transgenose, INTRAGENE, Orléans, France |
Disease and phenotype information
MGI phenotypes (allele matching)
Literature references
- Mice heterozygous for a deletion of the tumor necrosis factor-alpha and lymphotoxin-alpha genes: biological importance of a nonlinear response of tumor necrosis factor-alpha to gene dosage.;Amiot F, Boussadia O, Cases S, Fitting C, Lebastard M, Cavaillon J M, Milon G, Dautry F, ;1997;European journal of immunology;27;1035-42; 9130661
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