C57BL/6NTac-Gldcem1H/H
Status | Available to order |
EMMA ID | EM:12534 |
International strain name | C57BL/6NTac-Gldcem1H/H |
Alternative name | GLDC-S956Y-EM1-B6N |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Gldcem1H |
Gene/Transgene symbol | Gldc |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:Not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References |
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Homozygous fertile | yes |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Atypical glycine encephalopathy / Orphanet_289863
- Neonatal glycine encephalopathy / Orphanet_289857
- Infantile glycine encephalopathy / Orphanet_289860
IMPC phenotypes (gene matching)
Literature references
- Regulation of glycine metabolism by the glycine cleavage system and conjugation pathway in mouse models of non-ketotic hyperglycinemia.;Leung Kit-Yi, De Castro Sandra C P, Santos Chloe, Savery Dawn, Prunty Helen, Gold-Diaz Diana, Bennett Stuart, Heales Simon, Copp Andrew J, Greene Nicholas D E, ;2020;Journal of inherited metabolic disease;43;1186-1198; 32743799
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