- abnormal heart morphology / IMPC
- enlarged spleen / IMPC
- abnormal eye morphology / IMPC
- abnormal heart looping / IMPC
- microphthalmia / IMPC
- prenatal lethality prior to heart atrial septation / IMPC
- persistence of hyaloid vascular system / IMPC
- abnormal embryo turning / IMPC
- abnormal pharyngeal arch morphology / IMPC
- abnormal vitelline vasculature morphology / IMPC
- abnormal placenta morphology / IMPC
- abnormal visceral yolk sac morphology / IMPC
- abnormal spleen morphology / IMPC
- decreased locomotor activity / IMPC
- eye hemorrhage / IMPC
- abnormal optic vesicle formation / IMPC
- embryonic growth retardation / IMPC
- preweaning lethality, complete penetrance / IMPC
- abnormal neural tube morphology / IMPC
- abnormal somite shape / IMPC
C57BL/6J-Vcanem1H/H
Status | Available to order |
EMMA ID | EM:12536 |
International strain name | C57BL/6J-Vcanem1H/H |
Alternative name | VCAN-E441A-EM1-B6 |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Vcanem1H |
Gene/Transgene symbol | Vcan |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:Not knownHeterozygous:None reported |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | yes |
Homozygous viable | not known |
Homozygous matings required | no |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Wagner disease / Orphanet_898
IMPC phenotypes (gene matching)
Information on how we integrate external resources can be found here
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