- increased heart rate / IMPC
- increased circulating sodium level / IMPC
- abnormal thymus morphology / IMPC
- enlarged thymus / IMPC
- abnormal retina morphology / IMPC
- hyperactivity / IMPC
- impaired glucose tolerance / IMPC
- decreased locomotor activity / IMPC
- abnormal tooth morphology / IMPC
- decreased body weight / IMPC
- increased prepulse inhibition / IMPC
- increased freezing behavior / IMPC
- abnormal spleen morphology / IMPC
- abnormal skin morphology / IMPC
- abnormal seminal vesicle morphology / IMPC
- abnormal heart left ventricle morphology / IMPC
- increased airway resistance / IMPC
- small heart / IMPC
- small spleen / IMPC
- abnormal inspiratory capacity / IMPC
- abnormal uterus morphology / IMPC
- abnormal heart morphology / IMPC
- increased anxiety-related response / IMPC
- enlarged uterus / IMPC
- increased lung elastance / IMPC
C57BL/6NTac-Prdm8em1H/H
Status | Available to order |
EMMA ID | EM:13023 |
International strain name | C57BL/6NTac-Prdm8em1H/H |
Alternative name | Prdm8-FLOX-EM1-B6N |
Strain type | Endonuclease-mediated |
Allele/Transgene symbol | Prdm8em1H |
Gene/Transgene symbol | Prdm8 |
Information from provider
Provider | MRC-Harwell |
Provider affiliation | Mammalian Genetics Unit, Mary Lyon Centre at MRC Harwell |
Genetic information | For detailed information on the genetic description of this strain, please have a look at this report. |
Phenotypic information | Homozygous:Unkown at this stage - are breeding homs currentlyHeterozygous:None |
Breeding history | Co-isogenic on original background |
References | None available |
Homozygous fertile | not known |
Homozygous viable | not known |
Homozygous matings required | not known |
Immunocompromised | not known |
Information from EMMA
Archiving centre | Mary Lyon Centre at MRC Harwell, Oxford, United Kingdom |
Disease and phenotype information
Orphanet associated rare diseases, based on orthologous gene matching
- Early-onset Lafora body disease / Orphanet_324290
IMPC phenotypes (gene matching)
Information on how we integrate external resources can be found here
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