C57BL/6J-Prps1em2H/H

Status

Available to order

EMMA IDEM:13029
International strain nameC57BL/6J-Prps1em2H/H
Alternative namePrps1-R214W-EM2-B6
Strain typeEndonuclease-mediated
Allele/Transgene symbolPrps1em2H
Gene/Transgene symbolPrps1

Information from provider

Provider MRC-Harwell
Provider affiliationMammalian Genetics Unit, Mary Lyon Centre at MRC Harwell
Genetic informationFor detailed information on the genetic description of this strain, please have a look at this report.
Phenotypic informationHomozygous:
Unknown

Heterozygous:
Possibly males not viable - having to IVF this one
Breeding historyCo-isogenic on original background
ReferencesNone available
Homozygous fertilenot known
Homozygous viablenot known
Homozygous matings requirednot known
Immunocompromisednot known

Information from EMMA

Archiving centreMary Lyon Centre at MRC Harwell, Oxford, United Kingdom

Disease and phenotype information

Orphanet associated rare diseases, based on orthologous gene matching

    • X-linked intellectual disability-limb spasticity-retinal dystrophy-diabetes insipidus syndrome / Orphanet_423479
    • Lethal ataxia with deafness and optic atrophy / Orphanet_1187
    • Severe phosphoribosylpyrophosphate synthetase superactivity / Orphanet_411543
    • X-linked non-syndromic sensorineural deafness type DFN / Orphanet_90625
    • X-linked Charcot-Marie-Tooth disease type 5 / Orphanet_99014
    • Mild phosphoribosylpyrophosphate synthetase superactivity / Orphanet_411536
IMPC phenotypes (gene matching)
  • preweaning lethality, complete penetrance / IMPC

Information on how we integrate external resources can be found here

Order

Availabilities

Requesting frozen sperm or embryos is generally advisable wherever possible, in order to minimise the shipment of live mice.

  • Frozen sperm. Delivered in 4 weeks (after paperwork in place). €1740*
  • Rederivation of mice from frozen stock, delivery time available upon request . €3880*
  • Tissue - Types of tissue, service fee and delivery time available upon request

Due to the dynamic nature of our processes strain availability may change at short notice. The local repository manager will advise you in these circumstances.

* In addition users have to cover all the shipping costs (including the cost for returning dry-shippers, where applicable), as well as a CRISPR surcharge.

More details on pricing and delivery times

Practical information

Genotyping protocol

Example health report
(Current health report will be provided later)

Material Transfer Agreement (MTA)
MTA will be issued after an order has been submitted.

EMMA conditions
Legally binding conditions for the transfer

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